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Dr. Nasir and Dr. Meyer awarded a new KEEN Topical Grant

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Dr. Mansoor Nasir (PI) and Dr. Eric Meyer (Co-PI) were recently awarded a $25,000 grant by Kern Family Foundation (KFF) to develop a model for dissemination of entrepreneurial mindset in biomedical engineering.

The two faculty were the recipients of Kern Entrepreneur Education Network (KEEN) Topical grant in 2014 through which they developed modules for several courses focusing on the entrepreneurial skill set. The modules used the Quantified-self and Wearables as a theme for implementation. Eric and Mansoor

The following year (2015) the two faculty received funds through the KEEN Topical Subnet grant to organize three half-day workshops. After the first workshop on LTU campus, Dr. Nasir and Dr. Meyer took the Quantified-self ‘Roadshow’ to Bucknell and Ohio Northern Universities, where faculty and students were introduced to Theory and Practice of entrepreneurship.

The focus of the new grant is to specifically focus on broadening the scope of dissemination beyond the network through creation of digital and media resources. The faculty will work to integrate the LTU BME materials into the digital platform currently being developed by the KFF.


Editorial: The Case for Entrepreneurship in Biomedical Engineering Education (Dr. Mansoor Nasir)

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Read it all here: Austin J Biomed Eng. 2014;1(2): 1.

WJR Interview (Dr. Eric Meyer and Dr. Mansoor Nasir)

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Dr. Meyer  Eric Meyer talkes to WJR

Click Here to listen to the WJR Interview: Eric Meyer

Dr. Mansoor Nasir talks about the Biomedical Engineering Senior Projects and the collaboration between Industrial Sponsor (Gorden Maniere – Advanced Amputee Solutions) and the Biomedical Engineering students.

Listen to this WJR interview: Mansoor Nasir







More interviews from Lawrence Tech BME Students featured on WJR:

Click Here:  Lindsay Petku  

Click Here:  Akaram Alsamarae


Of Biosensors: Telling Your POCs from LOCs and EIS from EC by Dr. Mansoor Nasir

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Dr. Mansoor Nasir

Dr. Mansoor Nasir

“Medical device” is a catch-all term that can include anything and everything from prosthetics and diagnostic instruments to imaging and therapeutic devices. Sometimes, these are also referred to as “biosensors.” However, the

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term biosensor is more commonly used for specific devices or techniques that can qualitatively and quantitatively detect targets of interest. The targets include pathogens, DNA or some other specific protein, or a molecule. Examples of some of the most widely used medical devices that also qualify as biosensors are pregnancy tests, glucose sensors, and environmental sensors.

Of the aforementioned example, pregnancy tests and glucose sensors also qualify as Point-of-Care (POC) diagnostic devices. POCs are all the rage these days. To many, they espouse images of Tricorders and other instruments that might show up in an episode of Star Trek (Trekkie here) in the hands of Dr. McCoy. However, to a ‘serious’ BME student, they represent medical devices that can do the testing and analyze and present the data onsite were patient is located. This could be under supervision of a medical practitioner but certainly, one of the reasons for the success of pregnancy tests and glucose sensors is their ease of use and easy interpretation of results by layfolk.

In the research community, another term that is commonly used for a type of biosensor is a Lab-on-a-Chip (LOC) device (also called Micro Total Analysis System or mTAS). While similar in concept to POCs, LOCs are more sophisticated in their architecture and sensing capabilities. The might include fluidic conduits (sometimes referred to as microfluidics) and a variety of sensing modalities, such as optical, electrical, electrochemical, or acoustic, to

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name a few. Some may also include instrumentation and signal conditioning components. The holy grail in LOCs is a complete platform that can take a raw sample, filter and separate it into constituents, and then selectively identify and/or analyze the target, all on a device no bigger than a credit card.

Figure 1. (Left) First commercially available Glucose Biosensor (YSI 23A)*. (Right) A 3mm-long glucose sensor under development at Lawrence Technological University in Dr. Kandaswamy’s lab. Notice the drive toward miniaturization.

Figure 1. (Left) First commercially available Glucose Biosensor (YSI 23A)*. (Right) A 3mm-long glucose sensor under development at Lawrence Technological University in Dr. Kandaswamy’s lab. Notice the drive toward miniaturization.

LOC devices are attractive in part because they can work with extremely small sample volumes and have very fast detection times. Integrating so many functionalities on a single platform is tremendously challenging and many such devices still require bulky pumps and instrumentation and the end result is almost never the size of a credit card.

This is nowhere truer than in the case of biosensors based on fluorescent tagging. While fluorescent sensors set the bar for high sensitivity for bio/molecular detection, they require bulky measurement setup. Perhaps more importantly, these sensors require the need to label the target with fluorescent molecules. This introduces a host of new issues, such as selectivity and non-specific binding, which can introduce error in measured signal. In many cases, the required reagents are also temperature or light sensitive. The result is that fluorescent biosensors are not cost effective and also not easily miniaturized. Here electrical biosensors have an advantage as they rely solely on the measurement of voltages or currents for detection. The main advantage for studying impedance biosensors is their ability to perform label-free detection. While there are many variations of electrical sensors, the mostly commonly used techniques measure change in impedance or conductivity in the presence of the target. Further information about the target can be elicited if the frequency is also varied while holding the amplitude of the electrical stimulus constant. This technique is called Electrical Impedance Spectroscopy (EIS).

Figure 2. The figure shows an example of an impedance-based sensor made by using a micromachined Plexiglas flow channel that interfaces with a glass slide with microfabricated gold electrodes. There are two inlets and one outlet. The flow-rate ratio between sheath (faster) and sample (slower) fluids controls the sensitivity of this sensor.

Figure 2. The figure shows an example of an impedance-based sensor made by using a micromachined Plexiglas flow channel that interfaces with a glass slide with microfabricated gold electrodes. There are two inlets and one outlet. The flow-rate ratio between sheath (faster) and sample (slower) fluids controls the sensitivity of this sensor.

My research interests lie in the area of EIS but combine it with microfluidic sensor technology with the goal of rapid identification of chemical and biological threats. By using microchannels with different architectures as well as changing the flow rates of laminar fluid streams, impedance sensors with tunable sensitivity can be achieved. Working on such projects requires expertise from a multidisciplinary team with expertise in surface modification, microfabrication, and bioinstrumentation. Future research efforts will focus on extending the detection to a multielectrode system for impedance-based imaging systems.

There is considerable potential for incorporating such ideas in classroom teaching. A new BME course (BME4093), offered in Spring 2013, will focus on with various medical device technologies, including commercialized products such as the glucose sensor. EIS research includes elements of circuit design, electrochemical (EC) response of electrodes in electrolytic solutions, as well as bioinstrumentation for signal amplification and filtering. Students in the Bioelectrical Engineering Physics course (BME 4503) offered this semester learned about the theory behind EIS. In short, impedance biosensors have the potential for not only the development of simple, label-free detection of biosensors but can also be valuable tools in teaching students about some fundamental principles of biosensing platforms based on electrical measurements.


Lawrence Tech wins $50,000 DENSO grant for Haptics

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Lawrence Technological University has been awarded $50,000 to fund Advanced Haptics for Automation and Control Systems. Dr. Mansoor Nasir, the PI of the grant, along with colleagues in Biomedical Engineering (Dr. Eric Meyer), Robotics (James Kern), Psychology (Dr. Franco Delogu) and Electrical Engineering (Dr. Nabih Jaber) will use this grant to built the capacity for Haptics research and education at LTU. The grant will be used to buy tools and instrumentation to expose LTU students to the area of Haptics which deals with the sense of touch. Haptics applications include the design, development and evaluation of human-computer interfaces in automotive, telesurgery and virtual reality.


As one of the world’s largest automotive suppliers with operations in 32 countries and regions, DENSO provides capabilities in research and design, development, manufacturing and delivery of advanced automotive technology, systems and components to the automotive industry.

2016 ASEE Annual Conference

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Tomorrow the biomedical engineering faculty will be representing Lawrence Technological University at the 2016 ASEE Annual Conference in New Orleans. They will be talking about some of  our most recent work and upcoming programs the program has to offer. Presentation topic will include:

Using Quantified Self as a Learning Tool to Engage Students in Entrepreneurially Minded Learning and Engineering Design [view paper] Dr. Michael J. Rust (Western New England University), Dr. Mansoor Nasir (Lawrence Technological University), and Dr. Eric G. Meyer (Lawrence Technological University)

A Nanotechnology Summer Camp for High School Students: Activities Design and Student Feedback [view paper] Dr. Liping Liu (Lawrence Technological University), Dr. Mansoor Nasir(Lawrence Technological University), Dr. Yawen Li (Lawrence Technological University), Dr. Selin Arslan (Lawrence Technological University), Dr. Changgong Zhou (Lawrence Technological University), and Dr. Hsiao-Ping H. Moore (Lawrenece Technological University)

Multidisciplinary Patient-Centered Capstone Senior Design Projects [view paper] Dr. Mansoor Nasir (Lawrence Technological University), Dr. Darrell K. Kleinke P.E. (University of Detroit Mercy), and Dr. Molly McClelland (University of Detroit Mercy)

Project-based Learning in a Forensic Engineering Course [view paper] Dr. Mansoor Nasir (Lawrence Technological University), Dr. Eric G Meyer (Lawrence Technological University), and Brian Thomas Weaver PE (Explico Engineering Co. )

Sensing Angular Kinematics by Embedding an Open-source Electronics Design Project into a Required Biomechanics Course [view paper]Dr. Eric G Meyer (Lawrence Technological University) and Dr. Brent L Ulrey (Western New England University)
Good Luck!

Qualified Self and the Entrepreneurial Mindset Webinar (May 16th, 2016)

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Keen-Tag-OnDarkKEEN Webinar Hosted by Dr. Eric Meyer and Dr. Mansoor Nasir

Monday, May 16, 2016
1:00 – 1:30 p.m.  EDT

Have you been looking for more ways to expand the learning of your students? Or maybe you are looking for a way to bridge together what students are learning and the real world entrepreneurial side that struggles to find its way into the classroom. Well for the answers to this questions and many others be sure to join us on this webinar focused on the entrepreneurial mindset.

Dr. Eric Meyer and Dr. Mansoor Nasir’s teaching approach is to give all students in biomedical engineering multiple opportunities to practice entrepreneurially minded learning (EML). Discover how they developed EML modules centered on the theme of Quantified-Self (QS) devices. The presenters will describe how this project has impacted their early faculty career development, led to course revisions, and is currently being utilized by faculty around the country.

All participants will be given access to the EML activities utilizing QS devices to implement in their own classrooms.

To reserve your spot make sure to register here.

Quantified-Self (QS) Roadshow – Bucknell Edition

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QS Roadshow 11/6/15Dr. Mansoor Nasir and Dr. Eric Meyer traveled to Bucknell University in beautiful Lewisburg, PA for the second QS Roadshow event on Nov. 6th, 2015. The workshop was attended by 9 faculty members from Lawrence Tech, Western New England (WNE)  and Bucknell Universities. The roadshow is part of a KEEN Topical Network Grant (PI: Dr. Mansoor Nasir) that is being leveraged to disseminate classroom resources for EML and student engagement around the QS theme. LTU is taking the lead in building the network of faculty and is sharing resources at a dedicated website


Dr. Nasir and Dr. Meyer introduced the learning modules focusing on Entrepreneurial Mindset  Learning (EML) from various engineering and science fields to the attending faculty.


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The Dean of College of Engineering at Bucknell, Dr. Keith Buffinton, talked about entrepreneurship at Bucknell and the many opportunities available to the students to bring their ideas to fruition. Dr. Michael Rust, an Associate Professor from the Biomedical Engineering program at WNE, presented the EML module that he developed for his Sophomore level Fundamentals of Biomedical Engineering course.

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The half-day event also included a fabulous presentation by a guest speaker, Michael Levan, who is the founder of a local startup venture, Novipod. He specifically talked about Organ Tracker which is an organ tracking and monitoring application that delivers high precision GPS location, temperature, light, shock, humidity, and pressure sensors to organ procurement organizations, labs, pharmacies, and hospitals. He also shared his experiences about entrepreneurship and in commercializing a new technology.

IMAG0347 (1)  novipod_Logo

The presentation was attended by 20 BME seniors from Bucknell. During the afternoon, the faculty toured the various maker lab facilities available to the Bucknell students.


The overall reception of the event was extremely positive and will foster future collaborations between the faculty from these universities.

BME-IDEA Conference

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Dr. Nasir presented a snapshot of entrepreneurship-minded learning modules that have been introduced in various courses in the LTU BME program at the BME-IDEA conference on October 7, 2015. The meeting was held at Tampa Marriot Waterside Hotel in conjunction with 2015 Annual BMES conference.

BME-IDEA was started in 2003 when a group of professors who were teaching design in a Biomedical Engineering department or program realized that there were common needs among them that were not being met by current conference offerings. The first BME-IDEA meeting was held in San Francisco in 2003 and the alliance has met annually or bi-annually ever since. Over the past decade BME-IDEA has grown to include over 120 university programs in the U.S. and abroad with a focus on teaching and mentoring of innovation and entrepreneurship in biomedical engineering. These meetings are a chance to share best practices and new ideas with other faculty who lead programs and courses in medical technology design. Many past attendees have indicated that this is their favorite meeting of the year.


BMES 2015 Annual Conference in Tampa

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Lawrence Tech faculty, Dr Mansoor Nasir and Dr. Jerry LeCarpentier attended the Annual Biomedical Engineering Society (BMES 2015) conference from Oct. 7-11 in Tampa, FL.

BMES2015 (3) BMES2015 (2)

Two seniors from the BME department, John Peponis and Fatmah Alhaji also accompanied them. Fatmah Alhaji presented a poster titled “Piezoelectric Actuator for Microfluidic Mixing Applications” that covered the research she did on Dr. Nasir’s seed grant during the summer.

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Lawrence Tech setup a booth in the exhibit to promote the new Masters of Science in Biomedical Engineering at LTU and the students also helped out with the booth. Overall it was a great experience for everyone with some excellent talks and panel discussions. The weather in Tampa was also not too shabby


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