Biomedical Faculty Entrepreneurial Mindset in Motion…

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LTU wins $40,000 grant for entrepreneurial education

Assistant Professor Eric Meyer of Lawrence Technological University (LTU) is the principal investigator for a $40,000 grant to foster the entrepreneurial mindset through the development of multidisciplinary engineering learning modules based in part on the “Quantified Self” social movement.

Eric and Mansoor

LTU Assistant Professor Mansoor Nasir, who teaches in the biomedical engineering program with Meyer, is the co-principal investigator. Faculty at Western New England University and Kettering University will collaborate on the research project.

The grant is from the Kern Family Foundation of Waukesha, Wisc. LTU is a member of the Kern Entrepreneur Education Network (KEEN).

The consumer electronics industry is rapidly introducing new sensors and data-logging systems that enable individuals to gain insights into their personal health and wellness through quantification and tracking of a variety of biomedical measures. Social networks such as Facebook and the fitness industry are also embracing the opportunities created by the “Quantified Self” social movement, according to Meyer.

The Kern Foundation grant will support the development of class modules that draw on “Quantified Self” metrics while focusing on the entrepreneurial skills of opportunity, problem definition, and communication. Innovative teaching best practice techniques of Active and Collaborative Learning (ACL) and Problem/Project Based Learning (PBL) will be used to develop multi-disciplinary, multi-level modules that address many of KEEN’s desired outcomes for students.

“This proposal aims to introduce these exciting trends to students at various academic levels of engineering undergraduate programs,” Meyer said.

Meyer is creating a module for his spring semester course, Biomedical Best Practices, and. Nasir is creating a module for his spring semester course, “Biomedical Device Design, which is related to this topic and entrepreneurial engineering. They will measure the impact on students through quizzes and surveys before and after the modules. During the summer Meyer and Nasir will work with professors at Kettering, and Western New England universities to create additional modules related to this topic that would be introduced in other courses (by corner). The courses will be designed for all four undergraduate years and will cover mechanical engineering, electrical engineering, biomedical engineering, and physiology courses. “We will then take the data from the different courses and all the modules that were developed and share that information with KEEN members and at conferences,” Meyer said.


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Once again we say…Welcome Back

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Front row: Interim Director Dr.Elin Jensen, Faculty Yawen Li, 2ndRow Administrative support Bridgett Bailiff, Faculty Dr. Eric Meyer, Dr. Mansoor Nasir, and Dr. Jeff Morrissette

The biomedical engineering and life science faculty have been busy this past summer implementing new activities and opportunities for our freshman through senior students.  Returning students have noticed that room E108 – Bioinstrumentation Lab now has a new look.  The biomechanics gait analysis laboratory has secured funding from the DENSO Foundation to support research in human and machine interaction (see story on page xx).  We are very excited about this collaboration with the electrical engineering and robotic engineering programs.  Freshman students are enjoying working in the new collaboration space in room E109.   When you are on your way to the Environmental Scanning Electron Microscope or the BioMEMS laboratories, stop by to check out the new learning environment.

The Life Science Advisory Board welcomes two new members.  Mrs. Janelle Schrot from Materilize (MIMICS suite) and Dr. Ren You from Terumo Heart Inc. We look forward to working with these members and organizations as we continue to improve and expand the biomedical engineering program.

Finally, the biomedical engineering program thanks all the students and alumni who accepted the invitation to participate in the focus group meetings in the spring semester.  The focus groups provided valuable input on the needs and expectations of program graduates.  The biomedical engineering program educational objectives articulate the expected capabilities of graduates 3 to 5 years after graduation and they are:

  1. Graduates of the BSBME program apply foundational sciences and a wide range of engineering principles in order to lead cross-functional teams developing, designing, and verifying the function of medical technologies and services.   
  2.  Graduates of the BSBME program conduct translational biomedical engineering research while adhering to government compliance requirements and regulatory protocols.
  3.  Graduates of the BSBME program exhibit and demand the highest ethical and safety standards in their research and profession.
  4.  Graduates of the BSBME program are contributing members of the profession and society, and stay informed of current research and professional developments through advanced graduate studies and life-long education.

Enjoy your fall semester and your journey in discovering Lawrence Technological University!

Dr. Eric Meyers says this might be of interest to you

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Please review. One of the listings requires a Master’s Degree. So you might not have one just yet, but it’s always good to know what employers are looking for…

Research Engineer – Orthopaedic Biomechanics – Henry Ford Hospital (Detroit, MI)

The motion analysis laboratory at Henry Ford Hospital is seeking a full-time research engineer. The ideal candidate will have a background in biomedical or mechanical engineering and a strong interest in the biomechanics of human movement. This individual will be involved with all aspects of research being conducted in the motion analysis laboratory. Responsibilities include project planning, patient testing, data analysis, statistical analysis, and manuscript preparation. A masters degree and experience in orthopaedic research, human movement analysis, sports biomechanics or motor control are desirable. Experience with computer programming or laboratory equipment design are desirable but not required.

The motion analysis laboratory includes a biplane x-ray digital imaging system for high-speed analysis of dynamic in-vivo joint function, two 1000 frame/s digital video cameras, a 5-camera 240 frame/s 3D video-motion analysis system, force platforms, EMG, and extensive computer hardware/software for data collection and visualization. Primary research interests are in orthopaedic/sports biomechanics as related to joint and soft-tissue function, disease, injury and repair.

The position is available immediately and will be filled as soon as an appropriate candidate is identified. Salary is competitive and based on experience with an excellent benefits package. Interested and qualified applicants should send a letter, curriculum vitae or resume, and names and contact information for at least three references to the address listed below. E-mail applications can be sent to the address listed below. Henry Ford Health System is an AA/EO Employer.

Michael J. Bey, PhD
Henry Ford Health System
Bone and Joint Center; ER2015
2799 W. Grand Blvd.
Detroit, MI 48202

Here is the Second posting…

Eric Rohr

Biomechanics Research Associate – Brooks Sports Human Performance Lab Seattle, WA

As our Biomechanics Research Associate, you’ll carry out the research and development of our footwear and apparel products, executing research projects to develop the best in class product in regards to performance, fit, comfort and injury prevention. You will become a resident expert of all the biomechanical and mechanical testing done in our state of the art Human Performance Lab, and will participate in development of new tools, methods and procedures that will streamline data analysis. You will participate in projects that will require collaborative work with the innovation, design, development, and merchandising teams to bring to life relevant consumer insights and integrate them into our product line, to provide running products that are desired by our customers.

Your Responsibilities:
§ Proficiency in lower extremity anatomy, physiology and biomechanics of running/walking
§ Understand basic running shoe design features and components preferred
§ Be responsible for biomechanical lab testing (3D motion analysis, high speed video, plantar pressure systems) including subject preparation, data collection, data analysis and development of reports using MS Office Suite software
§ Perform mechanical lab testing of polymeric materials, components, and product (shoes and apparel).
§ Update and expand database of all current Brooks biomechanics test methods and benchmark against industry standards
§ Improve existing test methods primarily via automation of data processing
§ Responsible for reporting validation test results to provide guidance and direction to the design, development, innovation and merchandising teams. This involves possessing the understanding and knowledge to correlate wear test, mechanical and biomechanical test results into a comprehensive understanding of the performance of our running products in relation to comfort, fit, efficiency, and injury prevention.
§ Assist in the development of new test procedures including multisegment foot models, full body modeling

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and other biomechanics models necessary to expand our testing abilities
§ Contribute to learning opportunities for the footwear team through periodic presentations of new research and developments in performance testing and biomechanics of footwear design
§ Contribute to visibility of lab expertise and developments through periodic tours and demonstrations
§ Participate in biomechanical projects to research new areas in footwear and apparel design and improve biomechanical performance of our products.

• M.Sc. in Biomechanics, or related field including Engineering, Kinesiology, Physiology, Exercise Science, Human Factors, or Ergonomics.
• 2-3 years’ experience in lieu of a graduate degree.
• Possess a thorough understanding of anatomy, physiology, biomechanics of running, biomechanical principles and experimental design and statistical methods.
• Demonstrate an understanding of performance and injury mechanisms for running.
• Experience in use of biomechanics systems for analyzing running/walking gait (3D mocap systems (Motion Analysis, Vicon, Qualysis), Visual 3D, plantar pressure systems (Novel, Tekscan))
• Experience in writing programs (matlab, visual 3D, Labview, C/C++) is a plus
• Exposure to industrial research experience is a plus.
• Knowledge of footwear and product creation processes is a plus
• Ability to work on multiple projects simultaneously
• Computer proficiency with office software; MS Word, Excel, Outlook, PowerPoint.
• Excellent verbal and written communication skills, demonstrating effective listening through concise, clear verbal and written communication.
• Excellent interpersonal skills that inspire and build trust resulting in effective working relationships across the company.
• Demonstration of innovation and initiative – always looking at improving our products and processes while also displaying a willingness to dive into the details and help out wherever necessary.
• Passionate participation in Brooks’ sports activities a plus, overridden by the ability to understand and empathize with the runner in order to develop loyal, engaging relationships with our customers and the Brooks community.
• Embraces and lives the Brooks values!

Please apply at:
Job Board Vanity URL

Specimen-Specific Computational Models of Ankle Sprains Produced in a Laboratory Setting

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Button, Feng Wei, Eric G. Meyer and Roger C. Haut

J Biomech Eng 135(4), 041001 doi:10.1115/1.4023521



The use of computational modeling to predict injury mechanisms and severity has recently been investigated, but few models report failure level ligament strains. The hypothesis of the study was that models built off neutral ankle experimental studies would generate the highest ligament strain at failure in the anterior deltoid ligament, comprised of the anterior tibiotalar ligament (ATiTL) and tibionavicular ligament (TiNL). For models built off everted ankle experimental studies the highest strain at failure would be developed in the anterior tibiofibular ligament (ATiFL). An additional objective of the study was to show that in these computational models ligament strain would be lower when modeling a partial versus complete ligament rupture experiment. To simulate a prior cadaver study in which six pairs of cadaver ankles underwent external rotation until gross failure, six specimen-specific models were built based on computed tomography (CT) scans from each specimen. The models were initially positioned with 20 deg dorsiflexion and either everted 20 deg or maintained at neutral to simulate the cadaver experiments. Then each model underwent dynamic external rotation up to the maximum angle at failure in the experiments, at which point the peak strains in the ligaments were calculated. Neutral ankle models predicted the average of highest strain in the ATiTL (29.1 ± 5.3%), correlating with the medial ankle sprains in the neutral cadaver experiments. Everted ankle models predicted the average of highest strain in the ATiFL (31.2 ± 4.3%) correlating with the high ankle sprains documented in everted experiments. Strains predicted for ligaments that suffered gross injuries were significantly higher than the strains in ligaments suffering only a partial tear. The correlation between strain and ligament damage demonstrates the potential for modeling to provide important information for the study of injury mechanisms and for aiding in treatment procedure.


Lawrence Tech Researchers Take Multifaceted Approach to Fixing Knees

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Yawen Li

Eric Meyer

Dr. Yawen Li and Dr. Eric Meyer
College of Engineering
Biomedical Engineering Faculty
Lawrence Technological University

Each year an estimated 200,000 people in the United States suffer
painful and potentially debilitating anterior cruciate ligament (ACL)
tears in their knees, and that number is growing annually. Researchers
at Lawrence Technological University are looking for better methods for
repairing the damage, as well as preventing the injuries from occurring
in the first place.

The ACL connects the femur and tibia in the knee and provides
stabilization during motion. ACL tears have become a common sports
injury that can signal the end of a season or even the end of an
athlete’s career. Such injuries are also common among the elderly.

Two LTU professors and their students are examining ways to reduce the
impact of this injury. Assistant Professor Eric Meyer believes a better
understanding of the biomechanical causes of ACL tears can reduce the
number of injuries, while Assistant Professor Yawen Li is using tissue
engineering to regenerate ACL ligament tissue that could make surgical
repairs both less invasive and more effective.

Read more…


Last spring, as they prepared to complete bachelor’s degrees in biomedical engineering at Lawrence Technological University (LTU), Kevin Roberts and Katelyn Fortin developed a shoe insert. The insert was made to help runners avoid shin splints and other injuries caused by putting too much weight on the heel when striking the pavement.
In keeping with LTU’s “theory and practice” approach to education, many engineering students create a product for their senior project. Mr. Roberts and Ms. Fortin studied trends in running-shoe sales, looked at the biomechanics of foot and ankle function, and consulted faculty advisor Eric Meyer about their idea for a training device that would help transfer more weight to the front of the foot. The students were focused on completing the project for graduation and were ready to leave it at that. “I just

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would have taken the grade and forgotten about the idea,” said Mr. Roberts.
That changed after a meeting last fall with Tech Highway consultant Paul Garko, an LTU alumnus who is part of the LTU Entrepreneurial Collaboratory. With his guidance, they developed a business plan and applied for a patent. “They got us to think about it as a sellable product,” said Mr. Roberts of the problem-solving approach the Collaboratory consultants provided. “They shaped the project in the direction it needed to go.”
Mr. Roberts and Ms. Fortin went back to the drawing board to resolve problems with the design and then tackled commercialization issues. Finalizing the design will take about a year, and then they hope to have a marketable product ready to show investors. As part of the Collaboratory’s emphasis on using a target customer to test the product under development, Mr. Garko found a running club whose members were willing to train with the shoe insert.

Read more…

Characterization of Occupant Lower Extremity Behavior During Moderate-to-High Speed Rear Impacts

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Characterization of Occupant Lower Extremity Behavior During Moderate-Eric Meyerto-High Speed Rear Impacts

Steven Rundell, Allison Guiang, Brian Weaver, Eric G. Meyer

Date Published: 2013-04-08

Paper Number: 2013-01-0222

DOI: 10.4271/2013-01-0222


Injury potential to the neck has been studied extensively for rear-end impacts. The capacity for injury to other body regions, such as the lower extremities, has not been previously explored. The objective of the current study was to characterize the forces and motions experienced in the lower extremities during moderate-to-high speed rear-end impacts.

The current study utilized publicly available rear-end crash tests. Forty-two 50 km/hour, 20% offset, 180° barrier rear-end impacts were used. The occupant lower extremity behavior was analyzed for 63 ATDs, and included 42 driver’s seats, 8 front passenger seats, and 13 right-rear seat scenarios.

Three consistent events were identified during each test, in the following sequence; 1. initial compressive femur force, 2. secondary tensile femur force, and 3. rearward pelvis acceleration peak. In addition to pelvic contact with the seatback, in some cases the loading in the femur was influenced by contact between the seat pan and the back of the tibia just below the knee. The larger, male occupants experienced higher magnitudes of femur compression as the vehicle was impacted from the rear. The smaller, female occupants experienced predominately femur tension. Pelvic acceleration data corroborated these findings. Femur forces were consistent between both legs, indicating that there was little torsion applied to ATDs during the rear-end crash tests.

The current study indicates that occupant anthropometry and seat pan geometry play a significant role in loading of the lower extremity in a rear-end impact.

For more information:

Changing sagittal plane body position during single-leg landings influences the risk of non-contact anterior cruciate ligament injury

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Eric Meyer
Yohei Shimokochi, Jatin P. Ambegaonkar, Eric G. Meyer, Sae Yong Lee, Sandra J. Shultz


Purpose: To examine the effects of different sagittal plane body positions during single-leg landings on biomechanics and muscle activation parameters associated with risk for anterior cruciate ligament (ACL) injury.

Methods: Twenty participants performed single-leg drop landings onto a force plate using the following landing styles: self-selected, leaning forward (LFL) and upright (URL). Lower extremity and trunk 3D biomechanics and lower extremity muscle activities were recorded using motion analysis and surface electromyography, respectively. Differences in landing styles were examined using 2-way Repeated-measures ANOVAs (sex × landing conditions) followed by Bonferroni pairwise comparisons.

Results: Participants demonstrated greater peak vertical ground reaction force, greater peak knee extensor moment, lesser plantar flexion, lesser or no hip extensor moments, and lesser medial and lateral gastrocnemius and lateral quadriceps muscle activations during URL than during LFL. These modifications of lower extremity biomechanics across landing conditions were similar between men and women.

Conclusions: Leaning forward while landing appears to protect the ACL by increasing the shock absorption capacity and knee flexion angles and decreasing anterior shear force due to the knee joint compression force and quadriceps muscle activation. Conversely, landing upright appears to be ACL harmful by increasing the post-impact force of landing and quadriceps muscle activity while decreasing knee flexion angles, all of which lead to a greater tibial anterior shear force and ACL loading. ACL injury prevention programs should include exercise regimens to improve sagittal plane body position control during landing motions.

For more information:

Knee Surgery, Sports Traumatology, Arthroscopy

April 2013, Volume 21, Issue 4, pp 888-897

BME Newsletter April 2013

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Sports Injury Prevention Using Subject-Specific Models by Dr. Eric G. Meyer

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If you are part of the recent Blue Devil varsity sports revival, if you played sports competitively in high school, or even if you enjoy a weekend game with a couple of friends or family members, there are pretty good chances that you’ve experienced something in common. In young adults (18-44 years old) musculoskeletal injuries are reported by 38% of the population per year. Sports-related injuries represent 10-19% of all the injuries treated in emergency rooms. Injuries to the ankle and knee, in specific, are the most frequent injuries in sports.

Figure 1

A tear of the anterior cruciate ligament (ACL) is a season-ending injury and occurs in over

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100,000 athletes/year in the US. A classic sign of an ACL tear is hearing a “pop” that occurs while landing, cutting or pivoting. Although most do not involve contact with another player, it is very difficult to determine the exact cause of these injuries. Similarly, ankle sprains account for 10-30% of sports injuries, but the proposed mechanism for a severe injury, the “high ankle sprain” could not (until very recently) be reproduced in the laboratory. Ligament sprains often occur due to excessive torque in the knee and ankle. Linear traction is necessary for athletic performance, but excessive rotational traction between the shoe and surface is a factor for these injuries. Because of the complex interaction between risk factors, body positioning and external loading, biomechanical research into injury mechanisms must involve multiple investigative strategies (Figure 1).

For the investigation of high ankle sprains due to rotational traction, our research has included cadaver, surrogate, in vivo and in silico (computer simulation) approaches. The most recent step was the development of a three-dimensional computer

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model of the anklethat can predict the amount of deformation (strain) occurring in each ligament (Figure 2) during a particular sports scenario. The ligaments undergoing the most strain vary for different ankle positions and loading mechanisms and may represent the structure most at risk for injury. This model was validated based on cadaver experiments and then used with video analysis to accurately predict the ankle injuries. A limitation of this study is that a generic ankle joint model was used to simulate each of these scenarios. There is tremendous natural anatomical variation, such as size differences between males and females, and geometric differences between people with high aches or flat feet. Therefore, the most cutting-edge research today is moving towards using subject-specific models that are based on CT & MRI images from each ankle joint.

Figure 2

Technology and computer software for processing medical images and running computer simulations have advanced tremendously in recent years. Lawrence Tech undergraduates will have the opportunity to experience this innovation in the newly updated Biomedical Engineering Computer Graphics Laboratory (BME 1201) starting in the 2012 spring semester. This course will utilize the MimicsSE software by Materialise (a company with its US headquarters in Plymouth, MI and employer to this issue’s Alumni Spotlight, Danielle Beski) to teach medical images processing and creation of 3D models.

The risk of knee and ankle sprains during sports is a very complex problem. But as our understanding of each risk factor and injury mechanism increases through multidisciplinary research, engineers can create new solutions and safer designs so that young and aging athletes can avoid injury and increase their enjoyment of sports.


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